Deciding whether follow-up studies have replicated findings in a preliminary large-scale "omics' study"
Applications
2014-12-09 v2 Methodology
Abstract
We propose a formal method to declare that findings from a primary study have been replicated in a follow-up study. Our proposal is appropriate for primary studies that involve large-scale searches for rare true positives (i.e. needles in a haystack). Our proposal assigns an -value to each finding; this is the lowest false discovery rate at which the finding can be called replicated. Examples are given and software is available.
Cite
@article{arxiv.1310.0606,
title = {Deciding whether follow-up studies have replicated findings in a preliminary large-scale "omics' study"},
author = {Ruth Heller and Marina Bogomolov and Yoav Benjamini},
journal= {arXiv preprint arXiv:1310.0606},
year = {2014}
}