Correlation between mutation pressure, selection pressure and occurrence of amino acids
Statistical Mechanics
2007-05-23 v1 q-bio
Abstract
We have found that the effective survival time of amino acids in organisms follows a power law with respect to frequency of their occurrence in genes. We have used mutation data matrix PAM1 PET91 to calculate selection pressure on each kind of amino acid. The results have been compared to MPM1 matrix (Mutation Probability Matrix) representing the pure mutational pressure in the Borrelia burgdorferi genome.The results are universal in the sense that the survival time of amino acids calculated from the higher order PAMk matrices (k>1) follows the same power law as in the case of PAM1 matrices.
Cite
@article{arxiv.cond-mat/0301214,
title = {Correlation between mutation pressure, selection pressure and occurrence of amino acids},
author = {A. Nowicka and P. Mackiewicz and M. Dudkiewicz and D. Mackiewicz and M. Kowalczuk and S. Cebrat and M. R. Dudek},
journal= {arXiv preprint arXiv:cond-mat/0301214},
year = {2007}
}
Comments
Submitted for The International Conference on Computational Science ICCS'03 (St. Petersburg and Melbourne)