One of the fundamental results used in observational cosmology is the distance duality relation (DDR), which relates the luminosity distance, DL, with angular diameter distance, DA, at a given redshift z. We employ the observed limits of this relation to constrain the coupling of axion like particles (ALPs) with photons. With our detailed 3D ALP-photon mixing simulation in standard ΛCDM universe and latest DDR limits observed in Holand \& Barros (2016) we limit the coupling constant gϕ≤6×10−13GeV−1(⟨B⟩MpcnG) for ALPs of mass ≤10−15 eV. The DDR observations can provide very stringent constraint on ALPs mixing in future. Also any deviation in DDR can be conventionally explained as photons decaying to axions or vice-versa.