Diels-Alder cycloadditions are efficient routes for the synthesis of cyclic organic compounds. There has been a long-standing discussion whether these reactions proceed via stepwise or concerted mechanisms. Here, we adopt a new experimental approach to explore the mechanistic details of the model polar cycloaddition of 2,3-dibromo-1,3-butadiene with propene ions by probing its conformational specificities in the entrance channel under single-collision conditions in the gas phase. Combining a conformationally controlled molecular beam with trapped ions, we find that both conformers of the diene, gauche and s-trans, are reactive with capture-limited reaction rates. Aided by quantum-chemical and quantum-capture calculations, this finding is rationalised by a simultaneous competition of concerted and stepwise reaction pathways, revealing an interesting mechanistic borderline case.
@article{arxiv.2107.13858,
title = {Conformer-specific polar cycloaddition of dibromobutadiene with trapped propene ions},
author = {Ardita Kilaj and Jia Wang and Patrik Stranak and Max Schwilk and Uxia Rivero and Lei Xu and O. Anatole von Lilienfeld and Jochen Küpper and Stefan Willitsch},
journal= {arXiv preprint arXiv:2107.13858},
year = {2021}
}