Comment: Microarrays, Empirical Bayes and the Two-Groups Model
Methodology
2008-08-06 v1
Abstract
Brad Efron's paper [arXiv:0808.0572] has inspired a return to the ideas behind Bayes, frequency and empirical Bayes. The latter preferably would not be limited to exchangeable models for the data and hyperparameters. Parallels are revealed between microarray analyses and profiling of hospitals, with advances suggesting more decision modeling for gene identification also. Then good multilevel and empirical Bayes models for random effects should be sought when regression toward the mean is anticipated.
Keywords
Cite
@article{arxiv.0808.0597,
title = {Comment: Microarrays, Empirical Bayes and the Two-Groups Model},
author = {Carl N. Morris},
journal= {arXiv preprint arXiv:0808.0597},
year = {2008}
}
Comments
Published in at http://dx.doi.org/10.1214/08-STS236D the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)