Tethered particle motion is an experimental technique to monitor conformational changes in single molecules of DNA in real time, by observing the position fluctuations of a micrometer-size particle attached to the DNA. This article reviews some recent work on theoretical problems inherent in the interpretation of TPM experiments, both in equilibrium and dynamical aspects.
@article{arxiv.0710.1048,
title = {Colloidal particle motion as a diagnostic of DNA conformational transitions},
author = {Philip C Nelson},
journal= {arXiv preprint arXiv:0710.1048},
year = {2007}
}
Comments
19pp. Accepted for publication in Curr Op Colloid Interf Science