Cobordism Classes and the Swampland

We argue that any proposed quantum theory of gravity with non-trivial cobordism classes in the space of configurations belongs to the Swampland. The argument is based on the assumption that there are no global symmetries in a consistent theory of quantum gravity. The triviality of the cobordism classes requires the existence of certain stringy defects that trivialize the potential cobordism classes. We provide evidence for this conjecture by identifying those defects demanded by this argument that could preserve supersymmetry, and predict the existence of new non-supersymmetric defects in string theory.