Broad-tailed force distributions and velocity ordering in a heterogeneous membrane model for collective cell migration
Biological Physics
2012-08-09 v1 Soft Condensed Matter
Cell Behavior
Abstract
Correlated velocity patterns and associated large length-scale transmission of traction forces have been observed in collective live cell migration as a response to a "wound". We argue that a simple physical model of a force-driven heterogeneous elastic membrane sliding over a viscous substrate can qualitatively explain a few experimentally observed facts: (i) the growth of velocity ordering which spreads from the wound boundary to the interior, (ii) the exponential tails of the traction force distributions, and (iii) the swirling pattern of velocities in the interior of the tissue.
Keywords
Cite
@article{arxiv.1203.4333,
title = {Broad-tailed force distributions and velocity ordering in a heterogeneous membrane model for collective cell migration},
author = {Tripti Bameta and Dipjyoti Das and Sumantra Sarkar and Dibyendu Das and Mandar M. Inamdar},
journal= {arXiv preprint arXiv:1203.4333},
year = {2012}
}
Comments
7 pages and 5 figures