Bioelectrical Interfaces Beyond Cellular Excitability: Cancer, Aging, and Gene Expression Reprogramming
Quantitative Methods
2025-04-02 v1 Biological Physics
Cell Behavior
Abstract
Bioelectrical interfaces represent a significant evolution in the intersection of nanotechnology and biophysics, offering new strategies for probing and influencing cellular processes. These systems capitalize on the subtle but powerful electric fields within living matter, potentially enabling applications beyond cellular excitability, ranging from targeted cancer therapies to interventions in genetic mechanisms and aging. This perspective article envisions the translation, development and application of next-generation solid-state bioelectrical interfaces and their transformative impact across several critical areas of medical research.
Keywords
Cite
@article{arxiv.2504.00872,
title = {Bioelectrical Interfaces Beyond Cellular Excitability: Cancer, Aging, and Gene Expression Reprogramming},
author = {Paolo Cadinu and Matthew Burgess and Catarina Franco Jones and Titouan Luciani and Marzia Iarossi and Manuel Schröter and Nako Nakatsuka and Mustafa B. A. Djamgoz and Gil Gonçalves and Paola Sanjuán-Alberte and Paula M. Mendes and Frankie J. Rawson and Malavika Nair and Michael Levin and Rosalia Moreddu},
journal= {arXiv preprint arXiv:2504.00872},
year = {2025}
}
Comments
27 pages, 2 figures