English

Averaging for a Fully-Coupled Piecewise Deterministic Markov Process in Infinite Dimension

Probability 2012-07-03 v2

Abstract

In this paper, we consider the generalized Hodgkin-Huxley model introduced by Austin in \cite{Austin}. This model describes the propagation of an action potential along the axon of a neuron at the scale of ion channels. Mathematically, this model is a fully-coupled Piecewise Deterministic Markov Process (PDMP) in infinite dimension. We introduce two time scales in this model in considering that some ion channels open and close at faster jump rates than others. We perform a slow-fast analysis of this model and prove that asymptotically this two time scales model reduces to the so called averaged model which is still a PDMP in infinite dimension for which we provide effective evolution equations and jump rates.

Keywords

Cite

@article{arxiv.1109.6581,
  title  = {Averaging for a Fully-Coupled Piecewise Deterministic Markov Process in Infinite Dimension},
  author = {Alexandre Genadot and Michèle Thieullen},
  journal= {arXiv preprint arXiv:1109.6581},
  year   = {2012}
}

Comments

23 pages, 1 figure

R2 v1 2026-06-21T19:12:41.707Z