English

An impossible utopia in distance geometry

Computational Geometry 2021-10-05 v1 Metric Geometry

Abstract

The Distance Geometry Problem asks for a realization of a given weighted graph in RK\mathbb{R}^K. Two variants of this problem, both originating from protein conformation, are based on a given vertex order (which abstracts the protein backbone). Both variants involve an element of discrete decision in the realization of the next vertex in the order using KK preceding (already realized) vertices. The difference between these variants is that one requires the KK preceding vertices to be contiguous. The presence of this constraint allows one to prove, via a combinatorial counting of the number of solutions, that the realization algorithm is fixed-parameter tractable. Its absence, on the other hand, makes it possible to efficiently construct the vertex order directly from the graph. Deriving a combinatorial counting method without using the contiguity requirement would therefore be desirable. In this paper we prove that, unfortunately, such a counting method cannot be devised in general.

Keywords

Cite

@article{arxiv.2110.01231,
  title  = {An impossible utopia in distance geometry},
  author = {Germano Abud and Jorge Alencar and Carlile Lavor and Leo Liberti and Antonio Mucherino},
  journal= {arXiv preprint arXiv:2110.01231},
  year   = {2021}
}
R2 v1 2026-06-24T06:35:48.356Z