Accelerating reionization constraints: An ANN-emulator framework for the SCRIPT Semi-numerical Model

Constraining the Epoch of Reionization (EoR) with physically motivated simulations is hampered by the high cost of conventional parameter inference. We present an efficient emulator-based framework that dramatically reduces this bottleneck for the photon-conserving semi-numerical code SCRIPT. Our approach combines (i) a reliable coarse-resolution MCMC to locate the high-likelihood region (exploiting the large-scale convergence of SCRIPT) with (ii) an adaptive, targeted sampling strategy to build a compact high-resolution training set for an artificial neural network based emulator of the model likelihood. With only $\approx 10^3$ high-resolution simulations, the trained emulators achieve excellent predictive accuracy ($R^2 \approx 0.97-0.99$) and, when embedded within an MCMC framework, reproduce posterior distributions from full high-resolution runs. Compared to conventional MCMC, our pipeline reduces the number of expensive simulations by a factor of $\sim 100$ and lowers total CPU cost by up to a factor of $\sim 70$, while retaining statistical fidelity. This computational speedup makes inference in much higher-dimensional models tractable (e.g., those needed to incorporate JWST and upcoming 21 cm datasets) and provides a general strategy for building efficient emulators for next generation of EoR constraints.