A thermodynamic switch for chromosome colocalization
Subcellular Processes
2008-09-30 v1
Abstract
A general model for the early recognition and colocalization of homologous DNA sequences is proposed. We show, on a thermodynamic ground, how the distance between two homologous DNA sequences is spontaneously regulated by the concentration and affinity of diffusible mediators binding them, which act as a switch between two phases corresponding to independence or colocalization of pairing regions.
Keywords
Cite
@article{arxiv.0809.4788,
title = {A thermodynamic switch for chromosome colocalization},
author = {M. Nicodemi and B. Panning and A. Prisco},
journal= {arXiv preprint arXiv:0809.4788},
year = {2008}
}