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A systematic assessment of Large Language Models for constructing two-level fractional factorial designs

Methodology 2026-03-13 v2 Computation

Abstract

Two-level fractional factorial designs permit the study multiple factors using a limited number of runs. Traditionally, these designs are obtained from catalogs available in standard textbooks or statistical software. However, modern Large Language Models (LLMs) can now produce two-level fractional factorial designs, but the quality of these designs has not been previously assessed. In this paper, we perform a systematic evaluation of two popular classes of LLMs, namely GPT and Gemini models, to construct two-level fractional factorial designs with 8, 16, and 32 runs, and 4 to 26 factors. To this end, we use prompting techniques to develop a high-quality set of design construction tasks for the LLMs. We compare the designs obtained by the LLMs with the best-known designs in terms of resolution and minimum aberration criteria. We show that the LLMs can effectively construct optimal 8-, 16-, and 32-run designs with up to eight factors.

Keywords

Cite

@article{arxiv.2512.17113,
  title  = {A systematic assessment of Large Language Models for constructing two-level fractional factorial designs},
  author = {Alan R. Vazquez and Kilian M. Rother and Marco V. Charles-Gonzalez},
  journal= {arXiv preprint arXiv:2512.17113},
  year   = {2026}
}

Comments

31 pages, 11 tables