A semi-quantitative equivalence for abstracting from fast reactions
Abstract
Semantic equivalences are used in process algebra to capture the notion of similar behaviour, and this paper proposes a semi-quantitative equivalence for a stochastic process algebra developed for biological modelling. We consider abstracting away from fast reactions as suggested by the Quasi-Steady-State Assumption. We define a fast-slow bisimilarity based on this idea. We also show congruence under an appropriate condition for the cooperation operator of Bio-PEPA. The condition requires that there is no synchronisation over fast actions, and this distinguishes fast-slow bisimilarity from weak bisimilarity. We also show congruence for an operator which extends the reactions available for a species. We characterise models for which it is only necessary to consider the matching of slow transitions and we illustrate the equivalence on two models of competitive inhibition.
Keywords
Cite
@article{arxiv.1109.1365,
title = {A semi-quantitative equivalence for abstracting from fast reactions},
author = {Vashti Galpin and Jane Hillston and Federica Ciocchetta},
journal= {arXiv preprint arXiv:1109.1365},
year = {2011}
}
Comments
In Proceedings CompMod 2011, arXiv:1109.1044