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A physical perspective to understand myelin. II. The physical origin of myelin development

Biological Physics 2022-03-25 v3

Abstract

The physical principle of myelin development is obtained from our previous study by explaining Peter's quadrant mystery: an external applied negative and positive E-field can promote and inhibit the growth of the inner tongue of the myelin sheath, respectively. In this study, this principle is considered as a fundamental hypothesis, named Hypothesis-E, to explain more phenomena about myelin development systematically. Specifically, the g-ratio and the fate of the Schwann cell's differentiation are explained in terms of E-field. Moreover, an experiment is proposed to validate this theory.

Keywords

Cite

@article{arxiv.2111.13689,
  title  = {A physical perspective to understand myelin. II. The physical origin of myelin development},
  author = {Yonghong Liu and Yapeng Zhang and Wenji Yue and Ran Zhu and Tianruo Guo and Fenglin Liu and Yubin Huang and Tianzhun Wu and Hao Wang},
  journal= {arXiv preprint arXiv:2111.13689},
  year   = {2022}
}