A PDE model for bleb formation and interaction with linker proteins
Analysis of PDEs
2019-12-20 v4 Cell Behavior
Abstract
The aim of this paper is to further develop mathematical models for bleb formation in cells, including cell-membrane interactions with linker proteins. This leads to nonlinear reaction-diffusion equations on a surface coupled to fluid dynamics in the bulk. We provide a detailed mathematical analysis and investigate some singular limits of the model, connecting it to previous literature. Moreover, we provide numerical simulations in different scenarios, confirming that the model can reproduce experimental results on bleb initation.
Keywords
Cite
@article{arxiv.1904.03474,
title = {A PDE model for bleb formation and interaction with linker proteins},
author = {Philipp Werner and Martin Burger and Jan-Frederik Pietschmann},
journal= {arXiv preprint arXiv:1904.03474},
year = {2019}
}