A New Algorithm for Protein Design
Condensed Matter
2009-10-28 v1 q-bio
Abstract
We apply a new approach to the reverse protein folding problem. Our method uses a minimization function in the design process which is different from the energy function used for folding. For a lattice model, we show that this new approach produces sequences that are likely to fold into desired structures. Our method is a significant improvement over previous attempts which used the energy function for designing sequences.
Cite
@article{arxiv.cond-mat/9508127,
title = {A New Algorithm for Protein Design},
author = {J. M. Deutsch and Tanya Kurosky},
journal= {arXiv preprint arXiv:cond-mat/9508127},
year = {2009}
}
Comments
10 pages latex 2.09 no figures. Use uufiles to decode