Trajectory prediction for traffic agents is critical for safe autonomous driving. However, achieving effective zero-shot generalization in previously unseen domains remains a significant challenge. Motivated by the consistent nature of kinematics across diverse domains, we aim to incorporate domain-invariant knowledge to enhance zero-shot trajectory prediction capabilities. The key challenges include: 1) effectively extracting domain-invariant scene representations, and 2) integrating invariant features with kinematic models to enable generalized predictions. To address these challenges, we propose a novel generalizable Physics-guided Causal Model (PCM), which comprises two core components: a Disentangled Scene Encoder, which adopts intervention-based disentanglement to extract domain-invariant features from scenes, and a CausalODE Decoder, which employs a causal attention mechanism to effectively integrate kinematic models with meaningful contextual information. Extensive experiments on real-world autonomous driving datasets demonstrate our method's superior zero-shot generalization performance in unseen cities, significantly outperforming competitive baselines. The source code is released at https://github.com/ZY-Zong/Physics-guided-Causal-Model.
@article{arxiv.2602.13936,
title = {A Generalizable Physics-guided Causal Model for Trajectory Prediction in Autonomous Driving},
author = {Zhenyu Zong and Yuchen Wang and Haohong Lin and Lu Gan and Huajie Shao},
journal= {arXiv preprint arXiv:2602.13936},
year = {2026}
}