English

3D ReX: Causal Explanations in 3D Neuroimaging Classification

Image and Video Processing 2025-04-30 v3 Artificial Intelligence Computer Vision and Pattern Recognition Machine Learning

Abstract

Explainability remains a significant problem for AI models in medical imaging, making it challenging for clinicians to trust AI-driven predictions. We introduce 3D ReX, the first causality-based post-hoc explainability tool for 3D models. 3D ReX uses the theory of actual causality to generate responsibility maps which highlight the regions most crucial to the model's decision. We test 3D ReX on a stroke detection model, providing insight into the spatial distribution of features relevant to stroke.

Cite

@article{arxiv.2502.12181,
  title  = {3D ReX: Causal Explanations in 3D Neuroimaging Classification},
  author = {Melane Navaratnarajah and Sophie A. Martin and David A. Kelly and Nathan Blake and Hana Chockler},
  journal= {arXiv preprint arXiv:2502.12181},
  year   = {2025}
}

Comments

Presented in the 2nd Workshop on Imageomics (Imageomics-AAAI-25), Discovering Biological Knowledge from Images using AI, held as part of AAAI-2025

R2 v1 2026-06-28T21:47:44.536Z