HomeMachine LearningarXiv:2605.29975

A Fully Convolutional Approach to Denoising Structural Dynamics Data from X-Ray Photon Correlation Spectroscopy

Machine Learningeess.SP2026-05v1license

Abstract

We present a fully convolutional denoising autoencoder (FC-DAE) for denoising two-time intensity-intensity correlation functions (C2C_2) in X-ray photon correlation spectroscopy (XPCS). Unlike conventional denoising autoencoders that are typically restricted to fixed input sizes, the FC-DAE accepts inputs of arbitrary dimensions while preserving correlation structures across diverse dynamical regimes. The model is trained using experimentally derived C2C_2 data collected at NSLS-II beamlines, with data augmentation applied to expand the diversity of the dataset and reduce overfitting. The FC-DAE successfully recovers intricate dynamical features in low signal-to-noise conditions while maintaining structural fidelity. To assess reconstruction reliability, we employ quantitative metrics to evaluate structural fidelity and identify potential model-induced bias. Our results demonstrate that the FC-DAE provides robust denoising performance with high computational efficiency, enabling recovery of XPCS dynamics under photon-limited and low-dose measurement conditions.

Cite

@article{arxiv.2605.29975,
  title  = {A Fully Convolutional Approach to Denoising Structural Dynamics Data from X-Ray Photon Correlation Spectroscopy},
  author = {Nisar Nellikunnummel and Andi Barbour and Lutz Wiegart and Tatiana Konstantinova and Anthony DeGennaro},
  journal= {arXiv preprint arXiv:2605.29975},
  year   = {2026}
}